You can add people automatically to your contacts when you reply to received email. Enable the plugin Automatic Contacts by going to Edit ▸ Plugins; click on Automatic Contacts so that it shows a check mark. Then go to Edit ▸ Preferences ▸ Contacts ▸ Automatic Contacts and enable the Create address book entries when sending emails option and select an address book in the drop-down field below that will receive the new contacts.
From now on, contacts will be automatically created for senders of received mail when you reply to that mail.
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